Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: response to amyloid-beta Molecular Function: small molecule binding
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
Tlr4
(Mus musculus)Gene
Name: toll-like receptor 4
Synonyms: lipopolysaccharide response, RAS-like, family 2, locus 8, Rasl2-8, Lps
Source: MGI:96824
Biotype: protein coding gene
PSEN1
(Homo sapiens)Gene
Name: presenilin 1
Synonyms: AD3, presenilin-1 isoform I-467, PS-1, FAD, ACNINV3, familial Alzheimer Disease, CMD1U, presenilin 1 (Alzheimer disease 3), presenilin-1, PSNL1, S182, PS1
Source: HGNC:9508
Biotype: protein coding gene
TLR4
(Homo sapiens)Gene
Name: toll like receptor 4
Synonyms: TLR-4, hToll, CD284, ARMD10, homolog of Drosophila toll, TOLL, toll-like receptor 4
Source: HGNC:11850
Biotype: protein coding gene
Fcgr2b
(Mus musculus)Gene
Name: Fc receptor, IgG, low affinity IIb
Synonyms: LyM-1, Fc[g]RII, RIKEN cDNA F630109E10 gene, lymphocyte antigen 17, Fcr-3, Fcr-2, AI528646, FcgRII, CD32, Ly-17, Fcgr2a, Fcgr2, Fc gamma RIIB, F630109E10Rik, Lym-1, Ly-m20, FcgammaRIIB2, expressed sequence AI528646, FCRII, lymphocyte antigen m20, Fc receptor, IgG, low affinity IIa, FcgammaRIIB, Fc-gamma receptor 2, Fc receptor, IgG, low affinity II, Fc-gamma receptor 3
Source: MGI:95499
Biotype: protein coding gene
ICAM1
(Homo sapiens)Gene
Name: intercellular adhesion molecule 1
Synonyms: P3.58, BB2, human rhinovirus receptor, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, ICAM-1, major group rhinovirus receptor, cell surface glycoprotein P3.58, CD54
Source: HGNC:5344
Biotype: protein coding gene
Ager
(Mus musculus)Gene
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Source: MGI:893592
Biotype: protein coding gene
Tnf
(Rattus norvegicus)Gene
Name: tumor necrosis factor
Synonyms: tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrosis factor (TNF superfamily, member 2), MGC124630, RATTNF, tumor necrosis factor-alpha, Tnfa, tumor necrosis factor-like, tumor necrosis factor alpha, tumor necrosis factor superfamily member 2, tumor necrosis factor superfamily, member 2, LOC103694380, cachectin
Source: RGD:3876
Biotype: protein coding gene
IGF1
(Homo sapiens)Gene
Name: insulin like growth factor 1
Synonyms: IGF-I, IGFI, insulin-like growth factor I, IGF-IB, IGF-IA, insulin-like growth factor 1 (somatomedin C), IGF, mechano growth factor, MGF, somatomedin-C, insulin-like growth factor IA, insulin-like growth factor IB, insulin-like growth factor 1, IGF1A
Source: HGNC:5464
Biotype: protein coding gene
GRM5
(Homo sapiens)Gene
Name: glutamate metabotropic receptor 5
Synonyms: mGlu5, glutamate receptor, metabotropic 5, metabotropic glutamate receptor 5 variant H, metabotropic glutamate receptor 5, metabotropic glutamate receptor 5 variant G, MGLUR5, GRM5 variant 9, PPP1R86, metabotropic glutamate receptor 5 variant F, GPRC1E
Source: HGNC:4597
Biotype: protein coding gene
GJA1
(Homo sapiens)Gene
Name: gap junction protein alpha 1
Synonyms: EKVP, gap junction membrane channel protein alpha 1, PPKCA, CMDR, gap junction alpha-1 protein, HSS, gap junction protein, alpha-like, CX43, GJAL, connexin-43, AVSD3, gap junction protein, alpha 1, 43kDa, ODDD, DFNB38, HLHS1, EKVP3, connexin 43, gap junction 43 kDa heart protein
Source: HGNC:4274
Biotype: protein coding gene
FOXO3
(Homo sapiens)Gene
Name: forkhead box O3
Synonyms: FOXO3A-, MGC12739, AF6q21, forkhead homolog (rhabdomyosarcoma) like 1, FKHRL1, DKFZp781A0677, forkhead in rhabdomyosarcoma-like 1, FOXO2, forkhead box O3A, forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1, forkhead box protein O3, MGC31925, FOXO3A, FKHRL1P2
Source: HGNC:3821
Biotype: protein coding gene
Psen1
(Mus musculus)Gene
Name: presenilin 1
Synonyms: alzheimer disease 3 homolog, PS-1, Ad3h, S182, presenilin-1, PS1
Source: MGI:1202717
Biotype: protein coding gene
Psen1
(Rattus norvegicus)Gene
Name: presenilin 1
Synonyms: PS-1, presenilin-1
Source: RGD:3425
Biotype: protein coding gene
Trem2
(Mus musculus)Gene
Name: triggering receptor expressed on myeloid cells 2
Synonyms: Trem2-Mia, Trem2-Mib, triggering receptor expressed on myeloid cells 2c, triggering receptor expressed on myeloid cells 2b, triggering receptor expressed on myeloid cells 2a, Trem2a, Trem2c, Trem2b
Source: MGI:1913150
Biotype: protein coding gene
Vcam1
(Mus musculus)Gene
Name: vascular cell adhesion molecule 1
Synonyms: VCAM1B, CD106, Vcam-1
Source: MGI:98926
Biotype: protein coding gene
CD36
(Homo sapiens)Gene
Name: CD36 molecule (CD36 blood group)
Synonyms: CD36 molecule (thrombospondin receptor), glycoprotein IIIb, SCARB3, platelet glycoprotein 4, PASIV, leukocyte differentiation antigen CD36, GP4, cluster determinant 36, fatty acid translocase, PAS-4 protein, CD36 molecule, CHDS7, GPIIIB, platelet glycoprotein IV, PAS IV, GPIV, FAT, GP3B, BDPLT10, CD36 antigen (collagen type I receptor, thrombospondin receptor), scavenger receptor class B, member 3
Source: HGNC:1663
Biotype: protein coding gene
Bcl2
(Rattus norvegicus)Gene
Name: BCL2, apoptosis regulator
Synonyms: Bcl-2, B cell lymphoma 2 associated oncogene, Bcl-2alpha, ENSRNOG00000067693, B-cell CLL/lymphoma 2, Bcl2-like protein, apoptosis regulator Bcl-2, B-cell leukemia/lymphoma 2, B cell leukemia/lymphoma 2
Source: RGD:2199
Biotype: protein coding gene
VCAM1
(Homo sapiens)Gene
Name: vascular cell adhesion molecule 1
Synonyms: MGC99561, INCAM-100, DKFZp779G2333, CD106 antigen, CD106, vascular cell adhesion protein 1
Source: HGNC:12663
Biotype: protein coding gene
Gja1
(Mus musculus)Gene
Name: gap junction protein, alpha 1
Synonyms: expressed sequence AU042049, AU042049, Cx43alpha1, AW546267, alpha 1 connexin, Cx43, connexin43, Cxnk1, Gja-1, connexin 43, expressed sequence AW546267, Cnx43
Source: MGI:95713
Biotype: protein coding gene
Icam1
(Rattus norvegicus)Gene
Name: intercellular adhesion molecule 1
Synonyms: ICAM, ICAM-1, CD54
Source: RGD:2857
Biotype: protein coding gene
TREM2
(Homo sapiens)Gene
Name: triggering receptor expressed on myeloid cells 2
Synonyms: TREM-2, PLOSL2, triggering receptor expressed on myeloid cells 2a, AD17, Trem2a, Trem2c, Trem2b, triggering receptor expressed on monocytes 2
Source: HGNC:17761
Biotype: protein coding gene
AGER
(Homo sapiens)Gene
Name: advanced glycosylation end-product specific receptor
Synonyms: RAGE isoform NtRAGE-delta, receptor for advanced glycation end-products variant 20, RAGE isoform sRAGE-delta, RAGE isoform delta, advanced glycosylation end product-specific receptor, SCARJ1, receptor for advanced glycosylation end products, sRAGE, RAGE, receptor for advanced glycosylation end-products, MGC22357, receptor for advanced glycation end-products
Source: HGNC:320
Biotype: protein coding gene
Foxo3
(Mus musculus)Gene
Name: forkhead box O3
Synonyms: RIKEN cDNA 2010203A17 gene, FKHRL1, C76856, RIKEN cDNA 1110048B16 gene, 2010203A17Rik, Foxo3a, 1110048B16Rik, expressed sequence C76856, Fkhrl1, Fkhr2
Source: MGI:1890081
Biotype: protein coding gene
Icam1
(Mus musculus)Gene
Name: intercellular adhesion molecule 1
Synonyms: lymphocyte antigen 47, MALA-2, ICAM, Ly-47, Icam-1, MGC:6195, CD54
Source: MGI:96392
Biotype: protein coding gene
BCL2L2
(Homo sapiens)Gene
Name: BCL2 like 2
Synonyms: apoptosis regulator BCL-W, BCLW, BCL-W, protein phosphatase 1, regulatory subunit 51, BCL2-like 2 protein, PPP1R51, bcl-2-like protein 2, BCL2-L-2, KIAA0271
Source: HGNC:995
Biotype: protein coding gene
BACE1
(Homo sapiens)Gene
Name: beta-secretase 1
Synonyms: aspartyl protease 2, ASP2, membrane-associated aspartic protease 2, beta-site APP-cleaving enzyme, FLJ90568, APP beta-secretase, beta-site amyloid precursor protein cleaving enzyme 1, KIAA1149, beta-secretase 1 precursor variant 1, transmembrane aspartic proteinase Asp2, beta-site amyloid beta A4 precursor protein-cleaving enzyme, beta-site APP-cleaving enzyme 1, asp 2, HSPC104, BACE, memapsin-2, beta-site APP cleaving enzyme 1
Source: HGNC:933
Biotype: protein coding gene
NGFR
(Homo sapiens)Gene
Name: nerve growth factor receptor
Synonyms: low affinity nerve growth factor receptor, p75NTR, low-affinity nerve growth factor receptor, CD271, low-affinity nerve growth factor receptor p75NGFR, NGF receptor, TNFR superfamily, member 16, low-affinity nerve growth factor receptor p75NGR, low affinity neurotrophin receptor p75NTR, p75(NTR), p75 ICD, TNFRSF16, tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR
Source: HGNC:7809
Biotype: protein coding gene
Bcl2l2
(Mus musculus)Gene
Name: BCL2-like 2
Synonyms: AW048834, expressed sequence AW048834, gene trap ROSA 41, bclw, Bclw, BCL-W, Bcl-w, Gtrosa41, Gtrgal2, BCL-WEL, gene trap ROSA b-gal 2, BCL-WS
Source: MGI:108052
Biotype: protein coding gene
Igf1
(Mus musculus)Gene
Name: insulin-like growth factor 1
Synonyms: RIKEN cDNA C730016P09 gene, Igf-I, C730016P09Rik, Igf-1, IGF
Source: MGI:96432
Biotype: protein coding gene
Grm5
(Mus musculus)Gene
Name: glutamate receptor, metabotropic 5
Synonyms: 6430542K11Rik, Glu5R, Gprc1e, G protein-coupled receptor, family C, group 1, member E, expressed sequence AI850523, RIKEN cDNA 6430542K11 gene, mGluR5, mGlur5, AI850523
Source: MGI:1351342
Biotype: protein coding gene
CACNB1
(Homo sapiens)Gene
Name: calcium voltage-gated channel auxiliary subunit beta 1
Synonyms: calcium channel, L type, beta 1 polypeptide, dihydropyridine-sensitive L-type, calcium channel beta-1 subunit, calcium channel voltage-dependent subunit beta 1, CAB1, MGC41896, CACNLB1, CCHLB1, calcium channel, voltage-dependent, beta 1 subunit, voltage-dependent L-type calcium channel subunit beta-1
Source: HGNC:1401
Biotype: protein coding gene
CASP4
(Homo sapiens)Gene
Name: caspase 4
Synonyms: Mih1, ICEREL-II, caspase 4, apoptosis-related cysteine peptidase, ICE(rel)II, protease ICH-2, TX, CASP-4, caspase 4, apoptosis-related cysteine protease, Mih1/TX, ICE(rel)-II, ICH-2, apoptotic cysteine protease Mih1/TX, caspase-4 isoform alpha, protease TX, caspase-4, ICE and Ced-3 homolog 2
Source: HGNC:1505
Biotype: protein coding gene
Bace1
(Mus musculus)Gene
Name: beta-site APP cleaving enzyme 1
Synonyms: expressed sequence C76936, Bace, C76936
Source: MGI:1346542
Biotype: protein coding gene
Ngfr
(Mus musculus)Gene
Name: nerve growth factor receptor (TNFR superfamily, member 16)
Synonyms: p75NGFR, p75NTR, LNGFR, RNNGFRR, Tnfrsf16, p75 neurotrophin receptor, p75
Source: MGI:97323
Biotype: protein coding gene
Tlr4
(Rattus norvegicus)Gene
Name: toll-like receptor 4
Synonyms: toll4
Source: RGD:3870
Biotype: protein coding gene
Casp4
(Rattus norvegicus)Gene
Name: caspase 4
Synonyms: caspase 4, apoptosis-related cysteine peptidase, MGC124949, caspase 11, Casp11
Source: RGD:621757
Biotype: protein coding gene
Tlr6
(Mus musculus)Gene
Name: toll-like receptor 6
Synonyms: Not Available
Source: MGI:1341296
Biotype: protein coding gene
Cacnb1
(Mus musculus)Gene
Name: calcium channel, voltage-dependent, beta 1 subunit
Synonyms: CAB1, Cchb1, Cchlb1, calcium channel, B1 subunit
Source: MGI:102522
Biotype: protein coding gene
Trem2
(Rattus norvegicus)Gene
Name: triggering receptor expressed on myeloid cells 2
Synonyms: Trem2-Mia, LOC301227, Trem2-Mib
Source: RGD:1309841
Biotype: protein coding gene
Cacnb1
(Rattus norvegicus)Gene
Name: calcium voltage-gated channel auxiliary subunit beta 1
Synonyms: calcium channel voltage-dependent subunit beta 1, CAB1, brain calcium channel beta 1 subunit, calcium channel beta 1 subunit, calcium channel, voltage-dependent, beta 1 subunit, calcium channel voltage-dependent beta 1 subunit, voltage-dependent L-type calcium channel subunit beta-1
Source: RGD:68382
Biotype: protein coding gene
CALCR
(Homo sapiens)Gene
Name: calcitonin receptor
Synonyms: CTR, CRT, CT-R, CTR1
Source: HGNC:1440
Biotype: protein coding gene
MIR200A
(Homo sapiens)Gene
Name: microRNA 200a
Synonyms: MIRN200A, mir-200a
Source: HGNC:31578
Biotype: ncRNA gene
MT-RNR2
(Homo sapiens)Gene
Name: mitochondrially encoded 16S rRNA
Synonyms: mitochondrially encoded 16S RNA, MTRNR2
Source: HGNC:7471
Biotype: rRNA gene
Fpr2
(Mus musculus)Gene
Name: formyl peptide receptor 2
Synonyms: Fprl1, Fpr-rs2, Lxa4r, formyl peptide receptor, related sequence 2, RGD1566044, RIKEN cDNA E330010I07 gene, E330010I07Rik, Alx, Fpr2l
Source: MGI:1278319
Biotype: protein coding gene
Lgmn
(Mus musculus)Gene
Name: legumain
Synonyms: AI746452, Prsc1, AU022324, protease, cysteine, 1, expressed sequence AU022324, preprolegumain, expressed sequence AI746452, AEP
Source: MGI:1330838
Biotype: protein coding gene
MIR106B
(Homo sapiens)Gene
Name: microRNA 106b
Synonyms: MIRN106B, mir-106b
Source: HGNC:31495
Biotype: ncRNA gene
RAMP3
(Homo sapiens)Gene
Name: receptor activity modifying protein 3
Synonyms: receptor-activity-modifying protein 3, calcitonin-receptor-like receptor activity-modifying protein 3, calcitonin receptor-like receptor activity modifying protein 3, receptor activity-modifying protein 3, CRLR activity-modifying protein 3, receptor (calcitonin) activity modifying protein 3, receptor (G protein-coupled) activity modifying protein 3
Source: HGNC:9845
Biotype: protein coding gene
LGMN
(Homo sapiens)Gene
Name: legumain
Synonyms: asparaginyl endopeptidase, PRSC1, cysteine protease 1, protease, cysteine, 1 (legumain), LGMN1, protease, cysteine 1, AEP
Source: HGNC:9472
Biotype: protein coding gene