Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: positive regulation of endothelial cell proliferation
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
F3
(Homo sapiens)Gene
Name: coagulation factor III, tissue factor
Synonyms: coagulation factor 3, CD142, TF, tissue factor, FLJ17960, thromboplastin, coagulation factor III (thromboplastin, tissue factor), TFA
Source: HGNC:3541
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
FGFR3
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 3
Synonyms: tyrosine kinase JTK4, JTK4, HSFGFR3EX, ACH, CEK2, fibroblast growth factor receptor 3 variant 4, achondroplasia, thanatophoric dwarfism, CD333, fibroblast growth factor receptor 3-S, hydroxyaryl-protein kinase, FGFR-3
Source: HGNC:3690
Biotype: protein coding gene
Stat3
(Mus musculus)Gene
Name: signal transducer and activator of transcription 3
Synonyms: RIKEN cDNA 1110034C02 gene, expressed sequence AW109958, 1110034C02Rik, Aprf, AW109958
Source: MGI:103038
Biotype: protein coding gene
IL10
(Homo sapiens)Gene
Name: interleukin 10
Synonyms: CSIF, MGC126450, MGC126451, TGIF, GVHDS, IL10A, T-cell growth inhibitory factor, cytokine synthesis inhibitory factor, interleukin-10, IL-10
Source: HGNC:5962
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, bone morphogenetic protein 4 preproprotein, BMP2B, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
AGTR1
(Homo sapiens)Gene
Name: angiotensin II receptor type 1
Synonyms: AT2R1A, angiotensin receptor 1, angiotensin II receptor, type 1, AT2R1, AT2R1B, type-1 angiotensin II receptor, HAT1R, AT1R, ATR1, AGTR1A, angiotensin receptor 1B, AT1 receptor, AGTR1B, type-1B angiotensin II receptor, AT1BR, AT1AR, AG2S, angiotensin II type-1 receptor, AT1B, AT1
Source: HGNC:336
Biotype: protein coding gene
NF1
(Homo sapiens)Gene
Name: neurofibromin 1
Synonyms: truncated neurofibromin 1, neurofibromin, WSS, DKFZp686J1293, FLJ21220, neurofibromatosis-related protein NF-1, neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease), NFNS, VRNF, neurofibromatosis 1
Source: HGNC:7765
Biotype: protein coding gene
Fgfr3
(Mus musculus)Gene
Name: fibroblast growth factor receptor 3
Synonyms: sam3, HBGFR, Fgfr-3
Source: MGI:95524
Biotype: protein coding gene
AKT1
(Homo sapiens)Gene
Name: AKT serine/threonine kinase 1
Synonyms: serine-threonine protein kinase, PRKBA, protein kinase B alpha, v-akt murine thymoma viral oncogene homolog 1, PKB, CWS6, MGC99656, AKT, PKB-ALPHA, RAC-alpha serine/threonine-protein kinase, AKT1m, RAC, proto-oncogene c-Akt, rac protein kinase alpha, RAC-PK-alpha, RAC-ALPHA, protein kinase B, PKB alpha, v-akt murine thymoma viral oncogene-like protein 1
Source: HGNC:391
Biotype: protein coding gene
PRKCA
(Homo sapiens)Gene
Name: protein kinase C alpha
Synonyms: AAG6, PKC-A, PKCI+/-, MGC129901, MGC129900, PKCalpha, PKC-alpha, PKCA, PRKACA, aging-associated gene 6, protein kinase C alpha type
Source: HGNC:9393
Biotype: protein coding gene
JUN
(Homo sapiens)Gene
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Synonyms: v-jun sarcoma virus 17 oncogene homolog, jun oncogene, AP1, enhancer-binding protein AP1, proto-oncogene c-Jun, AP-1, transcription factor AP-1, transcription factor AP-1 subunit Jun, cJUN, Jun activation domain binding protein, c-Jun, transcription factor Jun, activator protein 1, v-jun avian sarcoma virus 17 oncogene homolog, p39, jun proto-oncogene, proto-oncogene cJun
Source: HGNC:6204
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, expressed sequence AA673258, AA673258, Sir2alpha
Source: MGI:2135607
Biotype: protein coding gene
Akt1
(Mus musculus)Gene
Name: thymoma viral proto-oncogene 1
Synonyms: PKB/Akt, PKB, Akt, PKBalpha
Source: MGI:87986
Biotype: protein coding gene
Il10
(Mus musculus)Gene
Name: interleukin 10
Synonyms: IL10X, cytokine synthesis inhibitory factor, If2a, IL-10, Il-10
Source: MGI:96537
Biotype: protein coding gene
VEGFA
(Homo sapiens)Gene
Name: vascular endothelial growth factor A
Synonyms: MVCD1, VEGF, vascular endothelial growth factor, vascular endothelial growth factor A165, vascular endothelial growth factor A121, vascular endothelial growth factor A, long form, vascular permeability factor, MGC70609, VEGF-A, VPF, L-VEGF
Source: HGNC:12680
Biotype: protein coding gene
Ccl2
(Mus musculus)Gene
Name: C-C motif chemokine ligand 2
Synonyms: MCP-1, monocyte chemotactic protein, expressed sequence AI323594, small inducible gene JE, monocyte chemoattractant protein-1, small inducible cytokine A2, Sigje, MCP1, AI323594, SMC-CF, Scya2, HC11, MCAF
Source: MGI:98259
Biotype: protein coding gene
STAT3
(Homo sapiens)Gene
Name: signal transducer and activator of transcription 3
Synonyms: acute-phase response factor, ADMIO, signal transducer and activator of transcription 3 (acute-phase response factor), FLJ20882, MGC16063, ADMIO1, DNA-binding protein APRF, APRF, HIES
Source: HGNC:11364
Biotype: protein coding gene
Mtor
(Mus musculus)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: expressed sequence AI327068, AI327068, flat-top, RAFT1, 2610315D21Rik, flat, FKBP-rapamycin-associated protein FRAP, Frap1, mechanistic target of rapamycin (serine/threonine kinase), RAPT1, FK506 binding protein 12-rapamycin associated protein 1, RIKEN cDNA 2610315D21 gene
Source: MGI:1928394
Biotype: protein coding gene
SIRT6
(Homo sapiens)Gene
Name: sirtuin 6
Synonyms: NAD-dependent protein deacylase sirtuin-6, regulatory protein SIR2 homolog 6, sirtuin, NAD-dependent deacetylase sirtuin-6, SIR2-like protein 6, sirtuin type 6, hSIRT6, NAD-dependent protein deacetylase sirtuin-6, SIR2L6, sir2-related protein type 6
Source: HGNC:14934
Biotype: protein coding gene
Vegfa
(Mus musculus)Gene
Name: vascular endothelial growth factor A
Synonyms: Vegf, vascular endothelial growth factor, VEGF188, VEGF111, VEGF-A, VPF, VEGF120, VEGF164
Source: MGI:103178
Biotype: protein coding gene
IGF1
(Homo sapiens)Gene
Name: insulin like growth factor 1
Synonyms: IGF-I, IGFI, insulin-like growth factor I, IGF-IB, IGF-IA, insulin-like growth factor 1 (somatomedin C), IGF, mechano growth factor, MGF, somatomedin-C, insulin-like growth factor IA, insulin-like growth factor IB, insulin-like growth factor 1, IGF1A
Source: HGNC:5464
Biotype: protein coding gene
IGF2
(Homo sapiens)Gene
Name: insulin like growth factor 2
Synonyms: insulin-like growth factor 2 (somatomedin A), T3M-11-derived growth factor, FLJ22066, somatomedin A, preptin, putative insulin-like growth factor II associated protein, GRDF, C11orf43, FLJ44734, somatomedin-A, insulin-like growth factor type 2, PP9974, SRS3, INSIGF, insulin-like growth factor II, IGF-II
Source: HGNC:5466
Biotype: protein coding gene
ADAM17
(Homo sapiens)Gene
Name: ADAM metallopeptidase domain 17
Synonyms: ADAM 17, cartilage snake venom-like protease, a disintegrin and metalloproteinase domain 17, snake venom-like protease, TACE, TNF-alpha-converting enzyme, a disintegrin and metalloproteinase 17, TNF-alpha converting enzyme, TNF-alpha convertase, ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme), ADAM18, NISBD1, MGC71942, disintegrin and metalloproteinase domain-containing protein 17, TNF-alpha convertase enzyme, ADAM metallopeptidase domain 18, CSVP, NISBD, tumor necrosis factor, alpha, converting enzyme, CD156B
Source: HGNC:195
Biotype: protein coding gene
Scg2
(Mus musculus)Gene
Name: secretogranin II
Synonyms: Chgc, SgII, Chcg, chromogranin C
Source: MGI:103033
Biotype: protein coding gene
ARNT
(Homo sapiens)Gene
Name: aryl hydrocarbon receptor nuclear translocator
Synonyms: hypoxia-inducible factor 1-beta, ARNT1, hypoxia-inducible factor 1, beta subunit, hypoxia inducible factor 1 subunit beta, HIF-1beta, HIF1B, HIF-1-beta, class E basic helix-loop-helix protein 2, dioxin receptor, nuclear translocator, TANGO, bHLHe2, HIF1BETA, HIF1-beta
Source: HGNC:700
Biotype: protein coding gene
HIF1A
(Homo sapiens)Gene
Name: hypoxia inducible factor 1 subunit alpha
Synonyms: member of PAS superfamily 1, MOP1, hypoxia-inducible factor 1 alpha isoform I.3, HIF-1alpha, HIF-1-alpha, basic-helix-loop-helix-PAS protein MOP1, HIF1-ALPHA, HIF1, hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), member of PAS protein 1, ARNT-interacting protein, PASD8, hypoxia inducible factor 1 alpha subunit, bHLHe78, PAS domain-containing protein 8", "Class E basic helix-loop-helix protein 78", "Member of PAS protein 1, ARNT interacting protein, PAS domain-containing protein 8, HIF-1A, hypoxia-inducible factor1alpha, class E basic helix-loop-helix protein 78, hypoxia-inducible factor 1-alpha
Source: HGNC:4910
Biotype: protein coding gene
Igf2
(Mus musculus)Gene
Name: insulin-like growth factor 2
Synonyms: Peg2, M6pr, Igf-2, Igf-II, expressed sequence AL033362, RNIGF2, IGFII, Mpr, AL033362
Source: MGI:96434
Biotype: protein coding gene
GATA2
(Homo sapiens)Gene
Name: GATA binding protein 2
Synonyms: FLJ45948, DCML, NFE1B, MONOMAC, GATA-binding protein 2, IMD21, endothelial transcription factor GATA-2, MGC2306
Source: HGNC:4171
Biotype: protein coding gene
Gata2
(Mus musculus)Gene
Name: GATA binding protein 2
Synonyms: Gata-2
Source: MGI:95662
Biotype: protein coding gene
Arg1
(Mus musculus)Gene
Name: arginase, liver
Synonyms: PGIF, Arg-1, expressed sequence AI256583, AI, AI256583
Source: MGI:88070
Biotype: protein coding gene
Jun
(Mus musculus)Gene
Name: jun proto-oncogene
Synonyms: c-jun, Junc, Jun-C oncogene
Source: MGI:96646
Biotype: protein coding gene
Vip
(Mus musculus)Gene
Name: vasoactive intestinal polypeptide
Synonyms: vip/phi27, PHI, peptide histidine isoleucine
Source: MGI:98933
Biotype: protein coding gene
Fgf2
(Mus musculus)Gene
Name: fibroblast growth factor 2
Synonyms: Fgf-2, fibroblast growth factor, basic, Fgfb, bFGF, Fgf2a
Source: MGI:95516
Biotype: protein coding gene
MIR27B
(Homo sapiens)Gene
Name: microRNA 27b
Synonyms: miRNA27B, MIR-27b, MIRN27B
Source: HGNC:31614
Biotype: ncRNA gene
Prkca
(Mus musculus)Gene
Name: protein kinase C, alpha
Synonyms: AI875142, Pkca, expressed sequence AI875142
Source: MGI:97595
Biotype: protein coding gene
Agtr1a
(Mus musculus)Gene
Name: angiotensin II receptor, type 1a
Synonyms: Agtr1, AT1R, MGC:37610, AI551199, angiotensin receptor 1a, Angtr-1a, expressed sequence AI551199, RIKEN cDNA 1810074K20 gene, Agtr-1a, andiotensin receptor 1a, 1810074K20Rik, AT1A, AT1a, AT1, Agt1ar
Source: MGI:87964
Biotype: protein coding gene
F3
(Rattus norvegicus)Gene
Name: coagulation factor III, tissue factor
Synonyms: coagulation factor 3, TF, Coagulation factor III (thromboplastin tissue factor), tissue factor, MGC93621, coagulation factor III, coagulation factor III (thromboplastin, tissue factor)
Source: RGD:2587
Biotype: protein coding gene
HMGB1
(Homo sapiens)Gene
Name: high mobility group box 1
Synonyms: HMG3, high-mobility group box 1, high-mobility group (nonhistone chromosomal) protein 1, SBP-1, high mobility group protein 1, high mobility group protein B1, Sulfoglucuronyl carbohydrate binding protein, Amphoterin, HMG-1, DKFZp686A04236, HMG1
Source: HGNC:4983
Biotype: protein coding gene
NRAS
(Homo sapiens)Gene
Name: NRAS proto-oncogene, GTPase
Synonyms: N-ras, NRAS1, neuroblastoma RAS viral oncogene homolog, neuroblastoma RAS viral (v-ras) oncogene homolog, v-ras neuroblastoma RAS viral oncogene homolog, N-ras protein part 4, GTPase NRas, NS6, CMNS, transforming protein N-Ras, ALPS4, KRAS, proto-oncogene GTPase, NCMS
Source: HGNC:7989
Biotype: protein coding gene
Fgf10
(Mus musculus)Gene
Name: fibroblast growth factor 10
Synonyms: expressed sequence BB213776, Gsfaey17, BB213776, gsf abnormal eyes 17, FGF-10, Fgf5a, AEY17
Source: MGI:1099809
Biotype: protein coding gene
KDR
(Homo sapiens)Gene
Name: kinase insert domain receptor
Synonyms: VEGFR2, protein-tyrosine kinase receptor Flk-1, fetal liver kinase 1, CD309, vascular endothelial growth factor receptor 2, VEGFR, soluble VEGFR2, tyrosine kinase growth factor receptor, fetal liver kinase-1, FLK1, kinase insert domain receptor (a type III receptor tyrosine kinase)
Source: HGNC:6307
Biotype: protein coding gene
FGFR1
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 1
Synonyms: FLG, basic fibroblast growth factor receptor 1, FLT2, Kallmann syndrome 2 (autosomal dominant), fms-related tyrosine kinase 2, HBGFR, HRTFDS, FLT-2, FGFR-1, BFGFR, FGFBR, bFGF-R-1, heparin-binding growth factor receptor, FMS-like tyrosine kinase 2, fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome), proto-oncogene c-Fgr, CD331, KAL2, N-SAM, soluble FGFR1 variant 2, soluble FGFR1 variant 1, FLJ99988, ECCL, CEK, FGFR1/PLAG1 fusion, OGD, hydroxyaryl-protein kinase, HH2
Source: HGNC:3688
Biotype: protein coding gene
Hmgb2
(Mus musculus)Gene
Name: high mobility group box 2
Synonyms: RGD1561694, C80539, HMG2, Hmg2, high mobility group protein 2, expressed sequence C80539, RGD1559962, RGD1564519, HMG-2
Source: MGI:96157
Biotype: protein coding gene
Akt1
(Rattus norvegicus)Gene
Name: AKT serine/threonine kinase 1
Synonyms: AKT1 kinase, protein kinase B alpha, PKB, v-akt murine thymoma viral oncogene homolog 1, thymoma viral proto-oncogene 1, Akt, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, Murine thymoma viral (v-akt) oncogene homolog 1, RAC protein kinase alpha, RAC-PK alpha, RAC protein kinase alpha RAC-PK alpha, PKB alpha, thymoma viral proto-oncogene, protein kinase B
Source: RGD:2081
Biotype: protein coding gene
Kdr
(Mus musculus)Gene
Name: kinase insert domain protein receptor
Synonyms: VEGFR2, orv, vascular endothelial growth factor receptor- 2, fetal liver kinase 1, VEGF receptor-2, Flk-1, Vegfr-2, VEGFR-2, orvieto, Flk1
Source: MGI:96683
Biotype: protein coding gene
Aplnr
(Mus musculus)Gene
Name: apelin receptor
Synonyms: Agtrl1, msr/apj, angiotensin receptor-like 1, Apj, APJ
Source: MGI:1346086
Biotype: protein coding gene
Hmox1
(Mus musculus)Gene
Name: heme oxygenase 1
Synonyms: DNA segment, Chr 8, Wayne State University 38, expressed, Heox, D8Wsu38e, HEOXG, Hsp32, hemoxygenase, Ho-1, HO-1, HO1, hsp32, Ho1, Hmox
Source: MGI:96163
Biotype: protein coding gene